Brett Favre passed for a season-high 392 yards and three touchdowns, and the Vikings intercepted Jay Cutler twice in a 36-10 victory over the Bears on Sunday.
Vince Young hit a leaping Kenny Britt for a 10-yard touchdown as time expired, and the Tennessee Titans rallied to beat the Arizona Cardinals 20-17 Sunday for their fifth straight victory.
Larry Johnson rushed for 107 yards in Cincinnati's conservative approach Sunday, and the Bengals completed their first division sweep with a 16-7 victory in their one-sided intrastate rivalry.
Compensating for the plantar fascia he battled for much of this season, New York quarterback Eli Manning has developed a stress reaction in his right foot that could be even more problematic for the Giants, according to sources close to the situation.
The Chargers turned four turnovers into touchdowns, including a 40-yard fumble return for a score by safety Paul Oliver, to beat the Kansas City Chiefs 43-14 on Sunday and run their winning streak to six games.
The NFL and NFL Players Association are finalizing a policy that would effectively prohibit a player from re-entering a game that he exits with a concussion-related injury.
Alex Smith threw short touchdown passes to Frank Gore and Vernon Davis and his solid outing in a 20-3 victory over the Jacksonville Jaguars on Sunday highlighted the kind of mistake-free day San Francisco coach Mike Singletary has sought for weeks.
Terrell Owens caught a 51-yard touchdown pass with 2:23 left to propel the Bills to a 31-14 win over the Dolphins Sunday and give interim coach Perry Fewell his first victory.
Darrelle Revis returned one of the Jets' four interceptions 67 yards for a touchdown and New York overcame an injury scare to quarterback Mark Sanchez before holding on to beat the Carolina Panthers 17-6 on Sunday.
Running back Steven Jackson is set to start the St. Louis Rams' game against the Seattle Seahawks after missing three days of practice with back spasms.